title banner

OR in the News

OR in the News (selected articles)

Tire, Yasin, Yazar, Mehmet Akif, Erdem, Said Sami Can changes in platelet count, mean platelet volume, and platelet distribution width be used to determine the severity of COVID-19?. Medical Science and Discovery 2021: 8 (10) 581-585

October 16, 2021

We aimed to investigate the relation of platelet count (PLT), mean platelet volume (MPV) and platelet distribution width (PDW) with other acute phase reactants in COVID-19 new corona virus.
Material and Methods:
Thirty one patients with COVID-19 were included in to study. There were three groups as outpatient (Group 1, OP) (n=6), hospital (Group 2, H) (n=16) and intensive care unit (Group 3, IC) (n=9) in this analytic study.
WBC (White Blood Cell), CRP (C-Reactive Protein) values were significantly different in all groups. PDW values were significantly lower in Group 3 than Group 1, 2. The result of ROC analysis was 10.9 as a cut-off value (Area under the curve, AUC)=0.407).
This study indicates that lower PDW may frequently develop in COVID-19 cases and there is a relation between thrombocytosis and acute phase reactants, that is, the inflammatory response. So we can offer that PDW should be used as a marker of Covid19 disease severity, but it needs more studies in the future.
Keywords: Mean platelet volume, Platelet count, Platelet distribution width, ARDS, COVID-19.