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Evaluation of the association between the optic nerve sheath diameter and extracorporeal life support time during cardiac surgery in newborns

June 17, 2023

OBJECTIVE:
Congenital heart disease (CHD), a birth defect, is a major cause of neonatal mortality; however, improvements in surgical procedures and medical treatments have resulted in decreased mortality rates. Nonetheless, postoperative morbidity, particu- larly cerebral dysfunction, remains an issue in patients receiving extracorporeal life support (ECLS) for cardiac surgeries. Herein, we aimed to assess the association between optic nerve sheath diameter (ONSD) and ECLS time in new- borns receiving ECLS for cardiac surgery.
PATIENTS AND METHODS:
We enrolled 25 newborn patients who received ECLS for cardi- ac surgery at our hospital. ONSD was measured at four different time points during the surgery: baseline (T1), 15 min after cross-clamping (T2), after displacement of cross-clamping (T3) and at the end of the surgery (T4). Furthermore, the ECLS time, aortic cross-clamp time, and surgery time were recorded.
RESULTS:
The regression analysis revealed a significant association between ONSD and ECLS time, cross-clamp time and surgery time. The correlation analysis showed strong associ- ations between baseline ONSD and ONSD at T2, T3, and T4. Moreover, ONSDs significantly in- creased at T2 compared with those at baseline during cardiac surgery.
CONCLUSIONS:
Our findings suggest an as – sociation between ONSD and ECLS time in new- borns receiving ECLS for cardiac surgery. Mon- itoring ONSD may provide valuable information about intracranial pressure changes in these pa- tients.