Devereaux PJ on behalf of the POISE-2 Investigators: Rationale and design of the PeriOperative ISchemic Evaluation-2 (POISE-2) trial: an international 2 x 2 factorial randomized controlled trial of acetyl-salicylic acid vs. placebo and clonidine vs. placebo in patients undergoing noncardiac surgery. Am Heart J 2014; 167: 804-9 e4
October 13, 2014
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