Jackson, C., Ikram, J., Diz Ferre, J. L., et al. | Clin Case Rep (2025) 13(4):e70454 | Anesthetic challenges of labor and delivery in a patient with catecholaminergic polymorphic ventricular tachycardia and left ventricular non-compaction cardiomyopathy- Outcomes Research Consortium

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Jackson, C., Ikram, J., Diz Ferre, J. L., et al. | Clin Case Rep (2025) 13(4):e70454 | Anesthetic challenges of labor and delivery in a patient with catecholaminergic polymorphic ventricular tachycardia and left ventricular non-compaction cardiomyopathy

November 29, 2025

Background: Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) and Left Ventricular Non-Compaction Cardiomyopathy (LVNC) are inherited disorders that pose significant challenges in the obstetric population because of the potential exacerbation of ventricular arrhythmias and potentially lethal cardiac compromise during pregnancy and labor.

Case Report: This case report provides insights into the anesthetic management of CPVT and LVNC in obstetric patients. Goals of management include careful optimization of anesthesia and analgesia, particularly during the birthing process. The choice of anesthetic agents, especially the avoidance of sympathomimetic drugs, is crucial in preventing catecholamine-induced arrhythmias. Additionally, the utilization of regional anesthesia techniques, such as epidural analgesia, may offer benefits in mitigating sympathetic activation during labor while providing adequate pain relief.

Conclusion: Close collaboration between obstetricians, anesthesiologists, and cardiologists is imperative to develop a comprehensive management plan tailored to the individual patient’s needs.